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  • H4: Develop future therapeutic technologies.
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According by these results, a titanium coated PEEK cage could be expected to provide the initial stability in postoperative results with having low incidence of expulsion compared to un-coated PEEK cage. Resume : Predicting the droplet state accurately is significant in manufacturing rough surfaces with superhydrophobic properties.

We use molecular dynamics simulation to investigate the static behavior of the water droplet on solid surfaces featuring pillared structures.

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Results show that the droplet in either the Wenzel state or the Cassie state depends on the height of the pillars and the pillar surface fraction. There is a critical point of the transition between the Cassie state and the Wenzel state when the height of the pillars and the pillar surface fraction changes.

The present study employs the TIP3P water model that has a single Lennard-Jones center representing an oxygen atom together with three charges, 0. The solid surface representing graphite with the characteristic surface energy of 0. The thermostat applied on the water molecules avoids the temperature rise caused by artificial vibration. To investigate the droplet static behavior and dynamic transition caused by vibration, the smooth surface and 15 types of rough surfaces are established. The water molecules are arranged on the rough solid surface as a rectangular block initially as shown in Fig.

All simulations are performed in two stages. The purpose in the first stage is to evaluate the nanostructure influence on the droplet state, the Wenzel or the Cassie. To achieve it, the computation is carried out for 1. Then, in the second stage the sinusoidal vibration with various amplitudes and frequencies is applied to the smooth and rough surface in the z direction. Especially on the rough surface, to investigate the dynamic state transition of the water droplet in the presence of vibration, a large number of simulations are performed and the thresholds are observed that could induce the transition from the Wenzel state to the Cassie state.

The static state of the water droplet in the Wenzel or Cassie state depends on the height of the pillars and the pillar surface fraction in the absence of vibration. For the low pillar surface fraction of case P3, the droplet is more inclined to be in the Wenzel state except that the height of pillars is greater than Conversely, if the pillar surface fraction is very large such as the case P1, the droplet will exhibit the Cassie state from a moderate height of 6.

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It can be found, there is a critical point of the transition from the Wenzel state to the Cassie state when the pillar surface fraction is 0. To the contrary, there also is a critical point of the transition from the Cassie state to the Wenzel state when the pillar surface fraction is 0. Resume : Chitosan CS and cellulose nanofibril CNF are well-known biopolymers which are prepared from the most abundant organic materials in nature of chitin and cellulose.

Hydroxyapatite HAp -CS composite known as a bone scaffold is mechanically weak in aqueous environments due to the swelling of CS so that it could not be used for applications such as an internal fixation device of bone fracture.

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Polylactic acid PLA derived from renewable resources such as sugar cane is biocompatible and biodegradable but brittle and become acidic when degraded. Mechanical properties such as flexural and tensile strength of the composite were tested.

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  4. And the composite was used for locking compression plate of internal fixation of bone fracture of a rabbit. Resume : Various types of transmembrane pores and ion channels in the range of nm are found in each biological cell, playing crucial roles in varieties of significant physiological activities such as maintaining cell osmotic balance and stabilizing cell volume.

    Resume : Porous microbeads synthesized by water—oil—water double emulsion solvent evaporation method show great potential as bio-carriers for bacteria attachment. Poly lactic-co-glycolic acid PLGA was chosen as a biodegradable and biocompatible candidate to fabricate the porous microbeads. The effect of concentration of ammonium bicarbonate and poly vinyl alcohol PVA as well as the surface modification technic were discussed here.

    Finally, the fluorescence bacteria were well attached to these porous microbeads. The confocal laser scanning microscopy CLSM was used to survey the inner porous structure without cutting of microbeads to obtain a cross-section image. The open structure porous microbeads whose surface was modified by NaOH solution were compared with non-open porous ones based on bacteria attachment.

    Resume : Recently, three-dimensional printing includes a wide variety of manufacturing techniques, which are all based on digitally-controlled depositing of materials layer-by-layer to create freeform geometries. We have developed an aqueous-solvent-based micro-molding technique for creating polymeric, bio-degradable micro-structures which can be loaded with delicate bioactive therapeutic agents.


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    The arrays of microneedles are integrated in an out-of-plane fashion with a base plate and can serve as patches for the release of drugs and vaccines. We used soft lithography and micro-molding to manufacture ceramic nanoporous. The process enables the incorporation of emerging protein based vaccines into sophisticated micro structures, e.

    As a demonstration, we successfully fabricated microneedles loaded with a peptide complex using a polydimethylsiloxane PDMS mold, including the parameters to be controlled. The process is proven to be capable of molding microneedles with sufficient sharpness down to 45?


    Resume : The discovery of graphene and its unique properties [1], has stimulated increasing interest in the study of materials with layered structures. Lead iodide, as a direct band gap semiconductor of about 2. Doping of PbI2 single crystals by transition metal TM elements Mn, Fe, Co etc with unfilled 3d-shell is of interest for the development of new materials- layered diluted magnetic semiconductors. In recent times, a number of research works have been reported on the synthesis of low-dimensional structures of PbI2:TM by physical and chemical methods.

    All low-dimensional structures, as similarly to for the bulk crystals, demonstrate anisotropy of properties and a strong exciton confinement.


    To probe this interaction, in addition to conventional UV-Vis absorption and photoluminescence spectroscopic methods we have used micro-Raman spectroscopy. It was shown the changes of protein luminescence spectra after adding of semiconductor nanoparticles in appropriate colloidal solution.

    These findings provide crucial information on a interaction of NPs with human blood components and significantly allows to extend the potential applications as the components of modern diagnostic systems. Geim A. Materials 6, Resume : Introduction: Placing eye prostheses after eye enucleation is often associated with eye infections. It is known that silver cations have antibacterial activity. They act as antioxidants, blocking cellular processes and leading to bacterial cell death. The principle of its action is to block the flow of oxygen to pathogenic microorganisms.

    Pathogenic microorganisms die quickly after contact with positive silver ions. These microorganisms do not develop colloidal silver resistance. In this aspect, silver particles have a stronger antibiotic effect. Purpose: Application of silver antibacterial nanoparticles on ocular dentures. Material and Methods: An ophthalmic prosthesis is made of two materials, transparent and dense.

    A specialized vacuum system for high frequency magnetron sputtering with argon carrier gas was used to apply silver nanopowder. The starting chamber pressure is Pa. The silver target used is of high purity silver sample The pattern is heated during deposition of the silver nanosilver to 50 degrees. Results: The obtained silver nanopowder is 12 nanometers thick on the experimental eye prosthesis specimen.

    An even nanosilver was observed on the test specimen, both on its transparent and on its non-transparent inner part. The antibacterial action of silver nanoparticles against gram positive, gram negative bacteria, as well as Candida albicans has been established. Conclusion: Antibacterial nanoparticle is applied for the first time on ocular dentures. Applying a silver anti-bacterial layer will reduce eye infections when inserting and using eye prostheses.

    Evaluation of cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticles. Med Microbiol Immunol. Antibacterial activity and mechanism of silver nanoparticles on Escherichia coli. Appl Microbiol Biotechnol. Resume : The development of low-molecular-mass oleogelators LMOGs that are able to entrap and structure oils has spurred growing interest in food, cosmetic and pharmaceutical industries in recent years.

    Oleogels that contain edible oils, such as soybean oil, sunflower oil, corn oil, olive oil, etc. Gels of petroleum-derived hydrocarbons are also appealing to the oil field industries for various applications, such as oil recovery and toxicity remediation devices. Recently, we have discovered some amino acid- derived LMOGs that can gelate a number of vegetable and mineral oils at low concentrations.

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    Furthermore, the LMOGs can efficiently uptake common fuel oils, such as petrol and kerosene from their biphasic mixture with water, thus showing great implement in the remediation of spilled oil from industrial wastewater. The properties of the oleogels, including morphology, thermal and mechanical stabilities will also be discussed in this oral presentation. Resume : Periodontitis is defined as a chronic inflammation resulting in irreversible destruction of the periodontium, which consists of the hard i.

    The design of scaffolds which mimic the complex periodontal shape and organization represents a significant challenge in regenerative periodontology. The mixture was conditioned as 3D porous scaffold by lyophilization. In order to evidentiate the microstructure of the biomimetic scaffold we used scanning electron microscopy SEM and immunohistochemistry for detection of CS and FN.

    Preliminary tests of their cytotoxicity in fibroblast gingival culture were performed by MTT assay. FN appears to be firmly attached to COL surface, suggesting the existence of interaction between these components. Resume : Bioactive molecules, though present in small quantities in foods and plants, are substances that provide great health benefits.